Krebs Cycle Pictures and Summary
As
the below diagram illustrates, this is truly a continuous cycle. Acetyl
coenzyme A binds to the oxaloacetate in order to convert it to citrate.
Water is released from the citrate and then regained in order to form
isocitrate. NAD+ binds to isocitrate, leaves as NADH, and carbon dioxide
is lost in order to form a-ketoglutarate. NAD+ binds to a-ketoglutarate,
leaves as NADH, coenzyme A binds and carbon dioxide is lost in order to
form succinyl CoA. Coenzyme A leaves in order to form succinate. FAD
binds to succinate and leaves as FADH2 in order to form fumarate. Water
binds to fumarate and forms malate. NAD binds to malate and leaves as
NADH which creates a new oxaloacetate molecule ready to bind to another
acetyl coenzyme A to start the process over again.
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